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LATEST NEWS IN MEDICINE
June, 18, 2019
New research in mice uncovers a previously unknown "pathway toward healthy aging." A circulating protein from the blood of young mice led to health improvements and visible signs of rejuvenation when researchers gave it to aging mice. As well as hair loss, wrinkles, and lessening mobility, less visible, underlying bodily changes also characterize the aging process.
One of these changes is the loss of a kind of "fuel" that keeps the body healthy — the so-called nicotinamide adenine dinucleotide (NAD).
May 15, 2019
An estimated 2.3 million people worldwide have MS, according to the National Multiple Sclerosis Society. The lack of a cure adds urgency to the quest to mitigate symptoms.
In recent years, cannabinoids — drugs that contain active components of cannabis — have garnered attention as a possible means of symptom relief. In 2014 guidelines, the American Academy of Neurology concluded that certain cannabinoids likely are effective for reducing some patient-reported symptoms, including spasticity and pain, but questions about the drugs’ efficacy remained.
A multi-institutional Spanish research group investigated the issue further with a systematic review and meta-analysis of studies published in JAMA Network Open. The researchers “aimed to evaluate the therapeutic efficacy and tolerability of medicinal cannabinoids to treat the symptoms of spasticity, pain and bladder dysfunction in patients with MS,” they wrote. Their study encompassed randomized, double-blind and placebo-controlled trials.
Zeroing In on Coffee’s Potential Use Against Neurodegenerative Disease
May, 15, 2019
The health effects of coffee are not a novel field of research. A study in Comprehensive Reviews in Food Science and Food Safety in 2016 determined that the benefits of moderate coffee consumption among adults clearly outweigh its risks, and numerous studies have evaluated its possible neuroprotective effects.
However, scientists are now placing additional focus on the mechanism behind those potential benefits. Canadian researchers recently discovered that phenylindanes in coffee inhibit the aggregation of both amyloid-beta and tau proteins, which contribute to the development of Parkinson’s and Alzheimer’s diseases.
The researchers examined how compounds in coffee affect proteins associated with neurodegenerative disease. The proteins they examined, while harmless as single proteins, become toxic to brain cells once they aggregate and clump together.